Alnylam Pharmaceuticals Inc.

Alnylam Pharmaceuticals Inc. is listed on NASDAQ (ALNY). We are a biopharmaceutical company seeking to develop and commercialize new drugs that work through a recently discovered system in cells known as RNA interference, or RNAi. We believe that drugs that work through RNA interference, or RNAi therapeutics, have the potential to become a major class of drugs, like small molecule, protein and antibody drugs. Using our intellectual property and the expertise we have built in RNAi, we are developing a set of biological and chemical methods and know-how that we expect to apply in a systematic way to develop RNAi therapeutics for a variety of diseases. We refer to these methods and their systematic application as our product engine. Using our current capabilities, we have initiated programs to develop RNAi therapeutics that will be administered directly to diseased parts of the body, which we refer to as Direct RNAitm therapeutics. We believe there are multiple opportunities for Direct RNAi therapeutics.

Alon USA Energy Inc.

Alon USA Energy Inc. is listed on NYSE (ALJ). ITEMS 1. AND 2. BUSINESS AND PROPERTIES. Statements in this Annual Report on Form 10-K, including those in Items 1 and 2, Business and Properties, and Item 3, Legal Proceedings, that are not historical in nature should be deemed forward looking statements that are inherently uncertain. See Forward-Looking Statements in Management’s Discussion and Analysis of Financial Condition and Results of Operations in Item 7 for a discussion of forward looking statements and of factors that could cause actual outcomes and results to differ materially from those projected. Company Overview In this document, the words we, our and us refer to Alon USA Energy, Inc. and its consolidated subsidiaries or to Alon USA Energy, Inc. or an individual subsidiary, and not to any other person. We are an independent refiner and marketer of petroleum products operating primarily in the Southwestern and South Central regions of the United States.

ASE Test Limited ..Limited is a Singapore holding company incorporated on December 1, 1995 as Jarich Test Private Limited, which changed its name to ASE Test Private Lim..

Atlantic BancGroup Inc ..ntic BancGroup, Inc. (Holding Company or Atlantic) was incorporated in the State of Florida. On April 3, 1999, the shareholders of Oceanside Bank (Oce..

Avalon Holdings Corporation .. April 30, 1998 as a subsidiary of American Waste Services, Inc. (AWS). Pursuant to the terms of a Contribution and Distribution Agreement dated as of..

American Express Company ..idated subsidiaries (American Express, the Company), is a leading provider of travel related services, payment services, financial advisory services a..

Brunswick Corporation ..ter of leading consumer brands, including: Mercury and Mariner outboard engines; MerCruiser sterndrive and inboard engines; MotorGuide trolling motors..

Berkshire Hathaway Inc. ..istrant) is a holding company owning subsidiaries engaged in a number of diverse business activities. The most important of these are insurance busine..

Bankrate Inc ..ments may contain forward-looking statements, including statements about our beliefs, plans, objectives, goals, expectations, estimates, projections a..

Berkshire Income Realty Inc. ..t on Form S-11 with the SEC with respect to its offers (the Offering) to exchange its 9% Series A Cumulative Redeemable Preferred Stock (Preferred Sha..

Biomet Inc. ..rporated in 1977, and its subsidiaries design, manufacture and market products used primarily by musculoskeletal medical specialists in both surgical ..

CTBI PFD CAP TR II ..ompany registered with the Board of Governors of the Federal Reserve System pursuant to Section 5(a) of the Bank Holding Company Act of 1956, as amend..

Britton & Koontz Capital Corporation .. as a Mississippi business corporation in July 1982. Later that year, the Company became a one-bank holding company registered under the Bank Holding ..

BOYKIN LODGING CO ..on, is a real estate investment trust (REIT) that as of March 11, 2005 owned interests in 24 hotels located throughout the United States. Boykin was f..

California First National Bancorp ..rporation , is a bank holding company headquartered in Orange County, California with leasing and bank subsidiaries. The Company has two leasing subsi..

Cambridge Display Technology Inc. ..company, CDT, we, us and our refer to Cambridge Display Technology, Inc. and its subsidiaries, unless the context otherwise requires. Our Company We a..

Community Banks Inc. ..as the Corporation or Community, is a financial holding company that was formed as a Pennsylvania corporation in 1982. Communitys banking subsidiary i..

Cedar Shopping Centers Inc ..4 and elected to be taxed as a real estate investment trust (REIT) in 1986. The Company is now a fully-integrated, self-administered and self-managed ..

CE Franklin Ltd. ..Canadian company (Franklin) completed its initial public offering and its shares were listed on the American Stock Exchange. CE Franklin is the result..

Computer Horizons Corp. ..s a strategic solutions and professional services company with more than thirty-seven years of experience, specifically in information technology. CHC..

CIT Group Inc (DEL) ..is a leading global commercial and consumer finance company. Founded in 1908, we provide financing and leasing capital for companies in a wide variety..

Calcasieu Real Estate ..na corporation organized in 1930 to receive non-producing mineral royalties spun off by a Southwest Louisiana bank. Over the years as some of the roya..

CMS Energy Corporation ..n energy holding company operating through subsidiaries in the United States and in selected markets around the world. Its two principal subsidiaries ..

Columbia Equity Trust Inc. ..ny refer to Columbia Equity Trust, Inc., a Maryland corporation, and our subsidiaries, including Columbia Equity, LP, a Virginia limited partnership (..

Cost Plus Inc. ..iler of casual home furnishings and entertaining products. As of January 29, 2005, the Company operated 237 stores under the name World Market, Cost P..

Carrizo Oil & Gas Inc. ..t energy company engaged in the exploration, development and production of natural gas and oil. Our current operations are focused in proven, producin..

City Network Inc. ..as incorporated in 1996 and develops hardware and software (total solution) for broadband communication solutions. We provide Internet broadband commu..

CommScope Inc. ..d manufacture of cable and connectivity solutions for communications networks. We focus on the last mile in communications networks, which is the dist..

Cabot Corporation ..ted in the State of Delaware in 1960. Cabot is a global specialty chemicals and performance materials company headquartered in Boston, Massachusetts. ..

CyberOptics Corporation .. Steven K. Case (Chairman of the Board of CyberOptics and full-time employee), a former professor at the University of Minnesota, with the goal of com..

DDi Corp. New .. printed circuit board engineering and manufacturing, and other value-added services. We specialize in engineering and fabricating complex multi-layer..

DECORIZE INC ..i, is a manufacturer and wholesaler of imported home furnishings and accessories. We founded decorize.com, LLC, the company that became Decorize, Inc...

DOMINION CNG CAP TR I .. all phases of the natural gas business, explores for and produces oil, and provides a variety of retail energy marketing services. The Company is a w..

Document Sciences Corporation ..d supports a family of Dynamic Content Publishing software products used primarily for business to customer communications. Dynamic content publishing..

Deutsche Bank AG ..utsche Bank Aktiengesellschaft. The original Deutsche Bank was founded in Berlin in 1870 as a joint stock company principally dedicated to financing f..

El Paso Corporation ..8 in El Paso, Texas. For many years, we served as a regional natural gas pipeline company conducting business mainly in the western United States. Fro..

Electro Energy Inc. ..h was originally formed on December 29, 1993 under the name MCG Diversified, Inc. (MCG). Effective June 9, 2004, pursuant to the Agreement of Merger a..

Electro-Sensors Inc. ..inct operating segments: (1) the manufacture and distribution of industrial production monitoring and process control systems through its Controls Div..

Elbit Systems Ltd. ..facture and integrate advanced, high-performance defense electronic and electro-optic systems for customers throughout the world. We focus on designin..

EntreMed Inc. ..maceutical company focused on developing the next generation of multi-mechanism oncology and anti-inflammatory drugs that target disease cells directl..

Electronic Arts Inc. ..istributes interactive software games that are playable by consumers on the following platforms: † Home videogame machines (such as the Sony PlayStati..

EXELON CORP ..y, through its subsidiaries, operates in three business segments—Energy Delivery, Generation and Enterprises—as described below. See Note 22 of Exelon..

Favrille Inc. ..research, development and commercialization of targeted immunotherapies for the treatment of cancer and diseases of the immune system. We have develop..

First Financial Holdings Inc. ..s a savings and loan holding company incorporated under Delaware law in 1987. The Company is headquartered in Charleston, South Carolina and operates ..

First Financial Corporation Indiana ..es holding company. The Corporation was originally organized as an Indiana corporation in 1984 to operate as a bank holding company. For more informat..

Fifth Third Bancorp .. about Fifth Third Bancorp and-or the company as combined with acquired entities within the meaning of Sections 27A of the Securities Act of 1933, as ..

First Oak Brook Bancshares Inc. ..der Delaware law in 1983 as a bank holding company under the Bank Holding Company Act of 1956, as amended. Effective May 26, 2004, the Company became ..

Redhook Ale Brewery Incorporated .. of the leading brewers of craft beers in the United States and has been at the forefront of the domestic craft brewing segment since the Company’s fo..

Geo Group Inc (The) .. and the Company refer to The GEO Group, Inc., its consolidated subsidiaries and its unconsolidated affiliates, unless otherwise expressly stated or t..

German American Bancorp Inc. ..olding company based in Jasper, Indiana. The Company’s Common Stock is traded on NASDAQ’s National Market System under the symbol GABC. The Company op..

Gilead Sciences Inc. ..n particular, statements about our expectations, beliefs, plans, objectives or assumptions of future events or performance are contained or incorporat..

General Maritime Corporation ..e crude oil transportation services. Our current fleet consists of 47 wholly owned tankers, consisting of 26 Aframax and 17 Suezmax tankers and four n..

Garmin Ltd. ..rmin) should be read in conjunction with, and is qualified by reference to, Management’s Discussion and Analysis of the Company’s Financial Condition ..

Genesis Energy L.P. ..ebsite our annual report on Form 10-K, quarterly reports on Form 10-Q, current reports on Form 8-K and amendments to those reports filed or furnished ..

HCC Insurance Holdings Inc. ..tion, which was formed in 1991. Its predecessor corporation was formed in 1974. Our principal executive offices are located at 13403 Northwest Freeway..

Hyperion Solutions Corporation ..er of business performance management (BPM) software. Hyperion’s software is used by large, global corporations to gain visibility into how their busi..

Hibbett Sporting Goods Inc. ..zed in 1945 under the name Dixie Supply Company in Florence, Alabama, in the marine and small aircraft business. In 1951, the Company started targetin..

Hooper Holmes Inc. ..olmes) currently engage in two principal businesses, which are operated as distinct divisions: • Our Health Information Division (HID), which we forme..

Heritage Commerce Corp ..orm 10-K may constitute forward looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the..

Industrias Bachoco S.A. de C.V. .. de C.V., and we frequently refer to ourselves commercially as Bachoco. We were incorporated in Mexico on April 17, 1980. Our headquarters are located..

IDT Corporation ..inment and technology company. Our primary telecommunications offerings are prepaid and rechargeable calling cards, wholesale carrier services and con..

II-VI Incorporated ..nsylvania in 1971. Our executive offices are located at 375 Saxonburg Boulevard, Saxonburg, Pennsylvania 16056. Our telephone number is 724-352-4455. ..

Innkeepers USA Trust ..stered real estate investment trust (REIT). Innkeepers owned 69 hotels with an aggregate of 8,684 rooms-suites (the Hotels) through its partnership in..

St. Joe Company (The) ..he terms we, JOE, Company and Registrant mean The St. Joe Company and its consolidated subsidiaries unless the context indicates otherwise. JOE is one..

Kitty Hawk Inc. New ..ently operate through our two wholly-owned subsidiaries, Kitty Hawk Cargo and Kitty Hawk Aircargo. Through Kitty Hawk Cargo, we operate a major indepe..

Lockheed Martin Corporation .., designs, develops, manufactures, integrates, operates and sustains advanced technology systems, products and services. We serve customers in domesti..

Mid-America Apartment Communities Inc. ..ith the Company’s Quarterly Reports on Form 10-Q, Current Reports on Form 8-K and any amendments to the aforementioned filings, are available on the C..