Orthofix International N.V.

Orthofix International N.V. is listed on NASDAQ (OFIX). In this Form 10-K, the terms we, us, our, Orthofix and our company refer to the combined operations of all of Orthofix International N.V. and its respective consolidated subsidiaries and affiliates, unless the context requires otherwise. For purposes of this Form 10-K, the subsidiaries of a person include all entities that such person controls. OVERVIEW We are a diversified orthopedic products company offering a broad line of minimally invasive surgical, as well as non-surgical, products for the spine, reconstruction and trauma market sectors. Our products are designed to address the lifelong bone-and-joint health needs of patients of all ages, helping them achieve a more active and mobile lifestyle. We design, develop, manufacture, market and distribute medical equipment used principally by musculoskeletal medical specialists for orthopedic applications.

Orthologic Corp.

Orthologic Corp. is listed on NASDAQ (OLGC). OrthoLogic is a drug development company focused on the healing of musculoskeletal, orthopedic, dermal and cardiovascular tissue through biopharmaceutical approaches. Our research is focused exclusively on the potential commercialization of our Chrysalin® Product Platform, a group of tissue healing product candidates based on Chrysalin (also known as TP508), a synthetic peptide. We purchased the exclusive worldwide license for Chrysalin for all medical indications on August 5, 2004 through our purchase of substantially all the assets and intellectual property of Chrysalis Biotechnology, Inc. (CBI). The acquisition significantly broadened our Chrysalin Product Platform, which now includes product candidates for 1) bone fracture repair, 2) dermal wound healing, 3) spine fusion, 4) cartilage defect repair, 5) cardiovascular repair, 6) dental bone repair and 7) ligament and tendon repair. We began operating as a development stage company upon the acquisition of CBI.

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